Lubiprostone_Human APIs Intermediate_Products_Shanghai Lianmin biologics Co., Ltd. 上海联民生物制品有限公司

Lubiprostone

地诺前列酮/前列腺素E2

20180720100544921

CAS No：363-24-6

Molecular Formula：C20H32O5

Molecular Weight：352.47

TEST	SPECIFICTIONS
Description	A white or almost white, crystals or crystalline powder
Identification	According to the requirements
Optical rotation	-90.0°~-82.0°
Congealing temperature	68℃
Loss on drying	≤2.0%
Water content	≤0.5%
15-Oxo-dinoprostone	≤1.0%
15-Epi-dinoprostone
8-Isodinoprostone
Dinoprostone related compound C	≤2.0%
(5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5, 10,13-triene-1-oic acid	≤1.0%
(5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5, 8(12),13-trien-1-oic acid	≤1.0%
Any individual unspecified impurity	≤0.1%
Residue solvents	Acetone≤0.5%
	Methanol≤0.3%
	Toluene≤0.089%
	Tetrahydrofuran≤0.072%
	Ethyl acetate≤0.5%
	Dichloromethane≤0.06%
Assay	97.0%~103.0%
Conclusion:	Complies with USP standards.